Neurological manifestations of COVID-19

• DOI: 10.22533/at.ed.6782026087

• Palavras-chave: Neurological; manifestations; COVID-19

• Keywords: Neurological; manifestations; COVID-19

• Abstract:

  Neurological manifestations of COVID-19

   

  Miguel Moni Guerra Cunha da Câmara¹, Caroline Sousa Araujo², Bruna Luanna Silva Lima³, Gabriel Lara Vasques⁴.

   

  ¹Medicine college, University of Rio Verde, Brazil. E-mail: [email protected]. Phone number: +55 64 99249-5000

  ²Medicine college, University of Rio Verde, Brazil. E-mail: [email protected]. Phone number: +55 62 9972-3876

  ³Medicine college, University of Rio Verde, Brazil. E-mail: [email protected]. Phone number: +55 62 99857-4338

  ⁴Advisor professor neurologist in medicine college of Rio Verde, Brazil, fellowship in clinical neurophisiology by the Neurological Institute of Goiânia. E-mail: [email protected]. Phone number: +55 62 8145-4547

   

  Abstract: The coronavirus disease 2019 (COVID-19) has represented certain mistery when talking about the manifestations, pathologycal action and disease-related-comorbities, mainly when talking about the nervous system. So far, the most related symptons were related with central nervous system, perypheral nervous system and skeletal muscle disease, besides cerebrovascular diseas such as ischemic stroke and acute cerebrovascular disease.

   

  Key-words: COVID-19; Neurological; Manifestations.

   

  Introduction

  The Coronavirus Disease 2019 (COVID-19) crisis has globaly emerged in the early months of 2020, overwhelming health systems and being a challenge to most societies from around the globe. Although the disease is still mysterious in certain issues, recent studies have defined some of the neurological manifestations of COVID-19, such as axonal perypheral neuropathy, myopathy, strokes and so many others.

  Methods

  This systematic literature review aims to synthesize the so far knowledge about neurological manifestations of COVID-19. Minding this objective, we have searched for: “Neurological manifestations of COVID-19” in The New England Journal of Medicine, Journal of the American Medical Association, The Lancet and PubMed Central. Due to the scarcity of researches about this theme, we have also used as database the International League Against Epilepsy, the European Stroke Organization, and the Brazilian Neurology Academy.

  Results

  Patients diagnosed with severe acute respiratory syndrome by infection of coronavirus 2 (SARS-Cov-2) presented central nervous system (dizziness and headache), perypheral nervous system (hypogeusia and hyposmia) and skeletal muscle symptons, besides Ischemic Stroke, impaired consciousness, ataxia, seizure, and acute cerebrovascular disease. It is suggested that the pathological mechanism happens due to the fact that SARS-CoV-2 enters the central nervous system via hematogenous or retrograde neuronal.

  Conclusion

  Patients with COVID-19 commonly have neurological manifestations. It is important to highlight that these symptons, are more present in more severe disease cases, where patients are older and have more comorbidities. There has been no evidence of direct effects of COVID -19 on seizures or epilepsy so far.

   

• Número de páginas: 2