LIVER METASTASECTOMY IN METASTATIC BREAST CANCER: REPORT OF TWO CASES AND LITERATURE REVIEW
LIVER METASTASECTOMY IN METASTATIC BREAST CANCER: REPORT OF TWO CASES AND LITERATURE REVIEW
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DOI: 10.22533/at.ed.94523181216
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Palavras-chave: Fatores de Risco Modificáveis, Promoção da Saúde, Custos de Saúde, Indicadores, Tecnologia da Informação, Metastasectomia Hepática
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Keywords: Modifiable Risk Factors, Health Promotion, Health Care Costs, Indicators, Information Technology, Liver Metastasectomy
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Abstract: Breast cancer is the most frequent neoplasm in women, with only 22% 5-year survival in metastatic disease. The hepatic metastasectomy, when eligible, showed an impact of 82 months on overall survival in patients submitted to the procedure. However, it is an alternative treatment still debatable in literature. In this study, two reports of metastatic breast cancer with surgical approach are discussed. Patient 1 had liver metastasis of initially triple negative invasive ductal breast carcinoma, but with metastatic immunohistochemistry HER-2 positive. Patient 2 presented hepatic metastasis of invasive ductal carcinoma luminal A, with immunohistochemistry compatible. Both patients underwent segmental hepatectomy associated with systemic chemotherapy. The reports presented reproduce favorable scenarios for metastasectomy, with good outcome of patients. The literature review, associated with the data from the reports, demonstrate a significant impact on overall survival when a surgical approach was performed.
- Rafael Martins Steffen
- Arthur Fernandes Pacheco
- Gabriela Camila Teixeira
- Bruna Alejandra Orellana Santos
- Marina Quaglio Oinegue Fulfaro