DRUG-DRUG INTERACTIONS IN INSTITUTIONALIZED PATIENTS WITH DEMENTIA

• DOI: 10.22533/at.ed.5782028018

• Palavras-chave: Atena

• Keywords: Drug interactions, dementia, Home for the Aged.

• Abstract:

  Concomitant use of drugs is the

  main factor involved in mutual interference

  reactions of pharmacological and toxicological

  actions and may result in numerous side effects

  and even potentially dangerous. Patients with

  dementia frequently use multiple medications,

  since they have a high level of comorbidities. In

  this way, they represent a group of great interest

  in the study of potential drug-drug interactions.

  This is a descriptive cross-sectional study which

  aimed to identify the main potential drug-drug

  interactions in institutionalized patient with

  dementia, especially the contraindicated and/

  or sever. Potential drug-drug interactions were

  identified and classified using Medscape Drug

  Interaction Checker® database. 155 interactions

  were cataloged. Of these, 26 (16.78%) are

  classified as severe, distributed among 30% of

  the patients (n=15). Thirty (60%) patients had at

  least one potential drug-drug interaction. Raising

  awareness and interventions aimed at reducing

  exposure and minimizing the risks associated

  with potentially harmful drug combinations

  are needed to ensure the best therapy for the

  patient.

• Número de páginas: 5