AVALIAÇÃO HISTOPATOLÓGICA DA CICATRIZAÇÃO DE PELE DE RATOS WISTAR TRATADOS COM EXTRATO AQUOSO DE CASCAS DE BANANA (Musa sp., CV. PRATA ANÃ)

• DOI: https://doi.org/10.22533/at.ed.6662412047

• Palavras-chave: cicatrização; fitoterapia; compostos fenólicos.

• Keywords: wound healing; phytotherapy; phenolic compounds

• Abstract: Banana (Musa sp.) is a common and abundant pseudofruit throughout the world, with extensive nutritional characteristics and low market and production value. The main by- product produced by banana consumption is the peels, with little market use. The peels have phenolic properties in large quantities that can be extracted and used in cosmetic and pharmacological products with the aim of regenerating and improving skin quality. A bibliographical search was carried out by consulting the MEDLINE, SciELO and Google Scholar databases. And in the experimental part, 32 animals were used divided into four groups, with eight animals in each group. The G1 Negative control group (C-) received a dressing with 0.9% saline solution; group G2 (CB), received a dressing with the aqueous extract gel of banana peels (Musa sp. , cv. Prata anã), group G3 (V), received a dressing with the gel containing only the vehicles used and the group G4 Positive control (C+), received a dressing with Dersani (sunflower oil). Assessment of treatment effects was carried out after 4, 7 and 14 days. It was possible to macroscopically observe wound closure in all groups and confirm with histopathology, greater wound repair on the 7th day of treatment, with many cells in the granulation tissue and intense vascularization, when compared to the negative control group.