USO EXCESSIVO DA SEMAGLUTIDA PARA EMAGRECIMENTO
USO EXCESSIVO DA SEMAGLUTIDA PARA EMAGRECIMENTO
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DOI: https://doi.org/10.22533/at.ed.1561325160415
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Palavras-chave: Semaglutida. Uso off-label. Automedicação.
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Keywords: Semaglutide. Off-label use. Self-medication.
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Abstract: The growing use of semaglutide for weight loss, especially in excessive amounts and without clinical indication, has raised concerns regarding public health risks. This literature review aimed to analyze the impacts of indiscriminate semaglutide use, addressing its mechanisms of action, adverse effects, and ethical challenges related to self-medication and off-label use. The methodology consisted of a systematic search in scientific databases, selecting studies published between 2020 and 2025 that discussed the inappropriate use of the drug. The results showed that, although semaglutide has proven efficacy in weight management and the treatment of type 2 diabetes, its use outside medical recommendations is associated with various adverse effects, including gastrointestinal disorders, pancreatitis, and renal complications. Furthermore, it was found that the influence of social media, the lack of professional guidance, and the ease of access to the medication contribute to the increase in irresponsible use. It is concluded that it is essential to strengthen pharmaceutical care, promote multidisciplinary follow-up, and implement awareness policies to ensure the safe use of semaglutide, preventing complications arising from its indiscriminate consumption.
- ELEN CRISTINA DE SOUZA
- EUGÊNIA HATSUE KATO