Triterpenos e saúde óssea: potencial terapêutico de Combretum leprosum Mart. na periodontite
Triterpenos e saúde óssea: potencial terapêutico de Combretum leprosum Mart. na periodontite
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DOI: https://doi.org/10.22533/at.ed.5722410094
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Palavras-chave: Combretum leprosum; Periodontite; Perda Óssea
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Keywords: Combretum leprosum; Periodontitis; Bone Loss
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Abstract: Among the diseases that affect bone metabolism, periodontitis is an immuno-inflammatory disease whose pathogenesis involves the host's response to a dysbiotic biofilm, which can lead to the progressive destruction of alveolar bone and tooth loss, compromising mastication, aesthetics, and quality of life. This chapter discusses the main experimental models used for the study of periodontitis, which are essential for understanding the disease and testing new treatments. Additionally, it addresses the medicinal role of plants, emphasizing the therapeutic potential of Combretum leprosum Mart., highlighting the value of one of its secondary metabolites, triterpenes, in bone health
- Erika Vanessa Farias dos Santos
- Jordânia Marques de Oliveira Freire
- Anderson Weiny Barbalho Silva
- Alana Nogueira Godinho
- Jair Mafezoli
- Francisco Geraldo Barbosa
- Hellíada Vasconcelos Chaves
- José Roberto Viana Silva
- Mirna Marques Bezerra Brayner
