SOFOROLIPÍDIOS DE Starmerella bombicola COMO ALTERNATIVA ANTIMICROBIANA PARA PEQUENOS ANIMAIS
SOFOROLIPÍDIOS DE Starmerella bombicola COMO ALTERNATIVA ANTIMICROBIANA PARA PEQUENOS ANIMAIS
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DOI: https://doi.org/10.22533/at.ed.81924090413
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Palavras-chave: Resistência microbiana; Dermatite atópica; Cães; Formulações antimicrobianas.
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Keywords: Antimicrobial resistance; Atopic dermatitis; Dogs; Antimicrobial formulations.
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Abstract: Canine atopic dermatitis (DAC) is a disease with high frequency among domestic animals, it has no cure and presents multifactorial origins. In general, medicines used to fight DAC, mainly anti-inflammatories and antibiotics, are prescribed for relief of the symptoms, including intense pruritus followed by skin lesions, which deeply compromise the animal welfare. Additionally, the raising of antimicrobial resistance and the zoonotic potential of methicillin-resistant Staphylococci (MRS) are alarming. Therefore, pursuing alternative antimicrobial molecules is indispensable to assist the fight against infections of epidermal lesions resulting from CAD. Biotechnological actives of natural origins, as sophorolipids, which are glycolipid biosurfactants, have been highlighted as ingredient to develop several industrial products. The notable antimicrobial activity of these biosurfactants constitute a practicable strategy to produce multifunctional formulas based in sophorolipids, which emerge as an important alternative for reducing CAD symptoms and promote animal welfare.
- Maria Antonia Pedrine Colabone Celligoi
- Nathalia Fraile Santana
- Flávia Eliza Staut Silva
- Franciely Grose Colodi
- Cristiani Baldo