MANEJO DA INFERTILIDADE EM MULHERES COM SÍNDROME DO OVÁRIO POLICÍSTICO: MECANISMOS, TRATAMENTOS E PERSPECTIVAS FUTURAS.
MANEJO DA INFERTILIDADE EM MULHERES COM SÍNDROME DO OVÁRIO POLICÍSTICO: MECANISMOS, TRATAMENTOS E PERSPECTIVAS FUTURAS.
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DOI: https://doi.org/10.22533/at.ed.798112521034
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Palavras-chave: Polycystic ovary syndrome; infertility; treatmen.
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Keywords: Polycystic ovary syndrome; infertility; treatmen.
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Abstract:
Polycystic Ovary Syndrome (PCOS) is one of the leading causes of female infertility, affecting up to 21% of women of reproductive age. This study investigated the pathophysiological mechanisms of PCOS-related infertility and the available therapeutic approaches. Insulin resistance and hyperandrogenism were identified as key factors in ovulatory dysfunction. Among the treatments analyzed, metformin demonstrated efficacy in restoring ovulation, while letrozole outperformed clomiphene in ovulation induction. Metabolic interventions, such as bariatric surgery and intermittent fasting, were also associated with improved fertility outcomes. Additionally, complementary therapies, including antioxidants and psychological support, contributed to better reproductive outcomes. It is concluded that the treatment of PCOS-related infertility should be multidisciplinary, combining pharmacological, metabolic, and emotional approaches to optimize results. Further research is needed to enhance the management of this condition and provide better prospects for affected patients
- Victor Monteiro Campos
- Pedro Paulo Augusto Carvalho de Almeida
- Paulo Eduardo Macedo de Moraes Filho
- Bruna Ferreira Di Palma Queiroz
- Luciano da Silva Lima
