Serratia marcescens: Uma Revisão Detalhada Sobre Características, Patogenicidade e Perspectivas Terapêuticas

• DOI: https://doi.org/10.22533/at.ed.246142513105

• Palavras-chave: -

• Keywords: -

• Abstract: Serratia marcescens is an opportunistic bacterium associated with nosocomial infections, especially in immunocompromised patients. It has a strong capacity to form biofilms on medical surfaces, such as catheters, which contributes to its persistence in hospital settings. Its main virulence factors include the production of red pigment (prodigiosin), extracellular enzymes (such as DNases, lipases, and proteases), and secretion systems that promote tissue invasion. Furthermore, it stands out for its resistance to multiple antibiotics, resulting from both intrinsic and acquired mechanisms, including efflux pumps and β-lactamase production. Because of these characteristics, S. marcescens is considered a pathogen of clinical relevance and a growing therapeutic challenge.