RELAÇÃO ENTRE O MICROBIOMA INTESTINAL E O SISTEMA ABO: UMA REVISÃO BIBLIOGRÁFICA
RELAÇÃO ENTRE O MICROBIOMA INTESTINAL E O SISTEMA ABO: UMA REVISÃO BIBLIOGRÁFICA
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DOI: 10.22533/at.ed.25224020110
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Palavras-chave: microbioma intestinal, ABO, populações, fatores genéticos
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Keywords: gut microbiome, ABO, populations, genetic factors
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Abstract: The gut microbiome is involved in several metabolic functions, being influenced by genetic, environmental and dietary factors. Variations in its composition can be beneficial to the host or cause inflammatory and metabolic diseases. ABO antigen and secretory status are known to be determinants for several diseases, many of which are also associated with the composition of the gut microbiome, and a relationship between gut bacteria and blood group may occur. The objective of this article was to develop a literature review on the influence of associations between the ABO system and gut bacteria on the microbiome composition. Studies in different populations in Europe and the United States (USA) demonstrate a close relationship between the composition of the microbiome with the ABO group and its secretory status. Populations with blood type A and antigen-secretors have been shown to have a wide variety of bacteria in their microbiome, showing an association of bacteria with the ABO and FUT2 genes. It was also observed abundance of genera that help to improve intestinal diseases such as Bifidobacterium and the Bacteroides genus, which can cause irritable bowel syndrome, depending on the type of association with the FUT2 gene. European populations have considerable variations in the microbiome that can affect the health of individuals. Thus, it is necessary to understand the relationship between the variation in the composition of the gut microbiome and the ABO group, thus being able to improve therapies for health maintenance.
- Isabela Maria do Nascimento
- Benedito Rodrigues da Silva Neto