PRINCIPAIS INTERAÇÕES COM ANTIBIÓTICOS

• DOI: https://doi.org/10.22533/at.ed.5122405045

• Palavras-chave: Interações medicamentosas, reações adversas, biotransformação, antibióticos.

• Keywords: drug interactions, adverse reactions, biotransformation, antibiotics.

• Abstract: The aim of this work is to expose the main interactions caused by the concomitant use of antibiotics and other allopathic medicines, nutrients and alcohol. It highlights the adverse effects, both beneficial and harmful (for the most part), and the detrimental effects on the patient's health, the effectiveness of the treatment, and in the case of hospitals, the high incidence of hospitalizations for an unnecessarily long time. In addition to the discomfort, the appearance of simultaneous pathologies, and the lack of control of pre-existing ones. In a simplified way, the topics present the most common cases, exemplifying the antimicrobial classes, their Drug Interactions (DIs) and the mechanisms that are susceptible to the mutual occurrence of action between two or more substances. The aim is to improve the quality of health care provided to individuals, in a conscious and responsible manner, playing a role in guiding and monitoring the patient, which guarantees their well-being. The research was carried out through a descriptive and qualitative literature review, gathering academic articles by authors who share similar results. Classes such as Penicillins, Cellosporins, Quinolones, Macrolides, among others, which are most used commercially and in hospitals, are also the most likely to interact with other substances in therapy. Therefore, concern during the medical consultation through to dispensing and adherence is the point that minimizes the possible risks that the patient can avoid if they follow and are correctly oriented.