PREVENÇÃO E CONTROLE DE Candida auris EM SERVIÇOS DE SAÚDE NO BRASIL: REVISÃO NARRATIVA DA LITERATURA

• DOI: https://doi.org/10.22533/at.ed.1642407033

• Palavras-chave: Candidíase, Multirresistência fúngica, Micologia, Brasil.

• Keywords: Candidíase, Fungal multidrug resistance, Mycology, Brazil.

• Abstract: Candida auris is a reemerging pathogenic yeast, capable of causing invasive nosocomial infections, has a potential for dissemination and significant multidrug resistance. Furthermore, it has a high mortality rate and is considered a serious global health problem. It was detected for the first time in 2009, where this yeast spread throughout the world with a presence in several countries. In December 2020, the first strain was isolated from a patient with COVID-19 in Brazil. The indiscriminate use of antifungal agents, such as fluconazole, may have been the factor responsible for the increased prevalence of infection and colonization by non-albicans Candida species. This study aims to review the scientific literature on the evidence on ways to prevent and control Candida auris in Brazil. This is a bibliographic study of the narrative literature review type with a qualitative approach, carried out in the databases: PUBMED, VHL, MEDLINE® and SCIELO, in the period of time from 2020 to December 2023. The descriptors in Health were crossed - DeCs: “Candida auris”, “Brazil” and “Communicable Disease Control” with Boolean operator AND. The final sample consisted of 05 articles that were carefully analyzed to prepare this review. Research indicates that there is intrinsic resistance to the main antifungal drugs, including Amphotericin B. The most affected patients are those who are immunosuppressed or have associated underlying pathologies. The main means of spreading the yeast C. auris is through sharing and failure to disinfect digital thermometers. Furthermore, there is a potential risk for the infection to worsen into candidemia with a mortality rate of 33.3%.