POTENCIAL CICATRIZANTE DE Passiflora ssp.: UMA REVISÃO SISTEMÁTICA
POTENCIAL CICATRIZANTE DE Passiflora ssp.: UMA REVISÃO SISTEMÁTICA
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DOI: https://doi.org/10.22533/at.ed.4332405027
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Palavras-chave: Cicatrização, Maracujá, Produtos Biológicos.
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Keywords: Cicatrization, Passion Fruit, Biological Products.
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Abstract: Currently, there is a growing interest in the study of natural products, especially those that are biologically safe and present themselves as by-products of the food industry and generate waste that would otherwise be discarded. In this context, those with multiple biological properties have stood out, including antioxidant, anti-inflammatory, antidiabetic, photoprotective potential, and healing activity, as is the case of Passiflora ssp. The present review aims to systematize the literature on the healing potential of Passiflora ssp. This systematic review wasdeveloped from the PubMed, Web Of Science and OpenGray databases, using the keywords “passion fruit” and “healing”, as well as their respective MeSH terms. The inclusion criteria were work carried out in an animal models, which aimed to evaluate the healing potential of Passiflora ssp. The search results totalled 45 articles. Of these, 9 met the criteria and were included in the present work. Few countries hosted the development of these investigations, and of the nine studies selected, the majority were carried out in Brazil. Regarding the parts of the plant used in the experiments, the majority used the leaves. The animal models adopted were rats, which received the intervention orally, intraperitoneally or cutaneously, alone or incorporated into biopolymers. Furthermore, the wounds considered in the studies were the result of diabetes, surgery or other pathological processes. The main conclusions included partial or complete wound healing during the studied period, occurring through increased fibroblast proliferation, as well as the antioxidant and anti-inflammatory activities of Passiflora ssp. However, few studies evaluating the healing potential of Passiflora ssp. have been developed to date. Therefore, new research must be carried out for this purpose, at the cellular level. in animals and humans, to obtain more robust results, to define the best dose, route and time of administration for healing different types of wounds.
- Marilene Brandão Tenório Fragoso
- Elaine Luiza Santos Soares de Mendonça
- Messias Oliveira da Silva
- Rafael Luis Barros de Oliveira
- Rosylene Portela Calheiros Lopes
- Iara Barros Valentim
- Marília Oliveira Fonseca Goulart
- Jadriane de Almeida Xavier