PERFIL ANTIOXIDANTE DA LUTEÍNA E ANÁLISE DE VISUALIZAÇÃO

• DOI: https://doi.org/10.22533/at.ed.71724170511

• Palavras-chave: Quelação, antioxidante, estresse oxidativo

• Keywords: Chelation, antioxidant, oxidative stress

• Abstract: Lutein, a dihydroxylated carotenoid belonging to the class of yellow-colored xanthophylls, acts as an antioxidant, protecting cells from oxidative damage and, consequently, reduces the risk of developing some chronic degenerative diseases, since oxidative stress and the action of free radicals are the major factors associated with the initiation and spread of the development of these diseases. The work aimed to evaluate the antioxidant profile of lutein and visualization analysis where DPPH and ORTHOPHENANTHROLINE (chelation and iron redaction) tests were carried out, which resulted in evidence of the antioxidant action of lutein on oxidation caused by free radicals, so that the lutein group demonstrated an IC50 of 0.2 µg/mL, similar to the IC50 of ascorboric acid of 0.2 µg/mL, showing that it is a potent natural antioxidant. The increase in the concentration of Fe2+ and Fe3+ showed inhibition in the reduction of oxidative stress. To validate these results, a scientometric study and visualization analyzes of descriptor networks were carried out as a research strategy and there were also DPPH tests, iron chelating evaluation and its reducing power in the compound lutein and, as mentioned, a scientometric study and data analysis that had chelation and antioxidant and oxidative stress as references and were researched in the research fields on the Scopus Platform (Elsevier) containing a large number of studies published between the years 2011 and 2021. scientometric evaluation, it was possible to observe the evolution of publications over the last 10 years and highlighting the years that had the most studies published.