PARTES VEGETAIS FOCADAS EM ESTUDOS ANTICÂNCER SOBRE ESPÉCIES MAIS INDICADAS NO SUDOESTE DE MATO GROSSO, BRASIL
Partes das plantas medicinais podem ter princípios ativos(p.a.) à terapia de câncer, hipótese a confirmar pela ciência. Este estudo revela partes anticâncer de cinco plantas mais recorrentes, conforme raizeiros do sudoeste de Mato Grosso(SW-MT, BRA) e literatura correspondente. A coleta de dados ocorreu entre jun.-set. 2015, em entrevistas com raizeiros(≥3/munic.), em 20 municípios do SW-MT(BRA), executadas pelo Grupo FLOBIO-UNEMAT/CNPq. Publicações sobre o potencial anticâncer destas plantas foram recuperadas, entre 27mar.-29jun.2016, no Google Acadêmico(GA), inserindo-se palavras-chave na caixa de pesquisa [tudonotítulo:nome científico, câncer]. As duas partes mais referidas por raizeiros(R=63) e nas publicações(P=54), das cinco espécies(Spi:5/63) mais mencionadas(60/154:38,9%) à terapia de câncer, foram: Sp1-Euphorbia tirucalli L. (R:10,3%;P:20,3%%): Haste/talo/galho-Htg (R:75,0%;P:27,2%), Látex/seiva-Las (R:66,6%;P:27,2%),; Sp2-Aloe vera (L.)Burm.f. (R:7,7%;P:37,0%): Folhas-Fo (R:77,7%;P:72,7%), Gel (R:33,3%; P:54,5%); Sp3-Synadenium grantii Hook.f. (R:8,4%; P:1,8%): Las (R:87,5%; P:0,0%), Raízes-Ra (R:0,0%; P:100%); Sp4-Croton urucurana Baillon (R:7,1%; P:3,7%): Las (R:83,3%; P:50,0%), Cec (R:16,6%; P:50,0%); Sp5-Annona muricata L. (R:5,1%; P:37,0%): Fo (R:71,4%; P:72,2%), Fruto-Fr (R:42,8%; P:27,2%). Das publicações recuperadas dessas cinco espécies, apenas 43 (79,6%) indicaram parte da planta analisada, destacando-se folhas (24/43:55,8%), hastes/talos/galhos (6/43:13,9%), cascas/entrecasca (6/43:13,9%), gel (6/43:13,9%), frutos (5/43:11,6%), látex (4/43:9,3%). As frequências de partes funcionais das plantas (npi: sustentação; respiração/fotossíntese-foliar; reprodutiva; circulatória/fluidal) referidas por raizeiros (R:60 menções) e as estudadas nas publicações (P:54 publicações), mostraram ser dependentes das espécies [(R:K2=59,90; GL=12; p<0,001); (P:K2=72,71;GL=12; p<0,001)]. As partes referidas à terapia de câncer dependem das espécies vegetais, cujos p.a. podem estar armazenados ou circulando na planta, a depender da espécie. Conclui-se que, as distintas partes anticâncer, referidas das plantas, variam com a espécie, predominando folhas no total. Os p.a. não estão em local padrão das plantas, variando conforme a espécie.
Palavras-chave: Plantas medicinais. Câncer, Raizeiros.
Apoio: UNEMAT, FAPEMAT, CNPq, CAPES, Colaboradores, Raizeiros
PARTES VEGETAIS FOCADAS EM ESTUDOS ANTICÂNCER SOBRE ESPÉCIES MAIS INDICADAS NO SUDOESTE DE MATO GROSSO, BRASIL
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DOI: 10.22533/at.ed.60321090820
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Palavras-chave: Plantas medicinais. Câncer, Raizeiros.
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Keywords: Medicinal plants. Cancer. Root doctors.
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Abstract:
Parts of medicinal plants may have active ingredients(a.i.) for use in cancer therapy - hypothesis to be confirmed by science. This study has addressed the parts of the five plants most frequently reported by root doctors from southwestern Mato Grosso(SW-MT,BRA) and in previous studies as having anticancer properties. Data collection took place between June and September 2015, using interviews with root doctors (≥3/munic.), in 20 municipalities in SW-MT(BRA), carried out by the FLOBIO-UNEMAT/CNPq Group. Between Mar.27-Jun.29-2016, publications on the anticancer potential of these plants were retrieved in Google Scholar(GS) by inserting keywords in the search box [allintitle:scientific name, cancer]. The two parts most referred to by root doctors(R=63) and in publications(P=54), of the five species(Spi:5/63) most frequently mentioned(60/154:38.9%) for cancer therapy, were: Sp1-Euphorbia tirucalli L. (R:10.3%;P:20.3%%): Stem/stalk/branch-Ssb (R:75.0%;P:27.2%), Latex/sap-Las (R:66.6%;P:27.2%); Sp2-Aloe vera (L.)Burm.f. (R:7.7%;P:37.0%): Leaves-Lvs (R:77.7%;P:72.72%), Gel (R:33.3%;P:54.5%); Sp3-Synadenium grantii Hook.f. (R:8.4%;P:1.8%): Las (R:87.5%;P:0.0%), Roots-Rts (R:0.0%;P:100%); Sp4-Croton urucurana Baillon (R:7.1%;P:3.7%): Las (R:83,3%;P:50,0%), Cec (R:16.6%;P:50.0%); Sp5-Annona muricata L. (R:5.1%;P:37.0%): Le (R:71.4%;P:72.2%), Fruit-Frt (R:42.8%;P:27.2%). After retrieval of the publications about these five species, it was found that only 43(79.6%) had mentioned the part plant being analyzed, with emphasis on leaves (24/43:55.8%), stems/stalks/branches (6/43:13.9%), Cec(6/43:13.9%), gel(6/43:13.9%), fruits(5/43:11.6%), latex(4/43:9.3%). The frequencies of mention of functional parts of plants (npi:support; respiration/leaf photosynthesis; reproduction; circulation/fluids), as reported by root doctors (R:60 mentions) and in publications (P:54 publications), proved to be species-dependent [(R:2=59.90; DF=12; p <0.001); (P:2=72.71; DF =12; p <0.001)]. The parts prescribed for cancer therapy vary according to plant species, whose a.i. may be stored or circulating in the plant, depending on the species. In conclusion, different parts of anticancer plants are prescribed, depending on the species, with an overall predominance of leaves. The active ingredients are not found in a fixed location in the plants; their location may vary from species to species.
Keywords: Medicinal plants. Cancer. Root doctors.
Support: UNEMAT, FAPEMAT, CNPq, CAPES, Collaborators, Root doctors
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Número de páginas: 22
- Fabiana Aparecida Caldart Rodrigues
- Arno Rieder
