Panorama dos Processos Oxidativos Avançados na Degradação de Sertralina
Panorama dos Processos Oxidativos Avançados na Degradação de Sertralina
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DOI: https://doi.org/10.22533/at.ed.2001125150411
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Palavras-chave: Processos oxidativos avançados, degradação de fármacos, sertralina.
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Keywords: “advanced oxidation processes”, “pharmaceutical degradation”, “sertraline”.
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Abstract: The presence of emerging contaminants, such as sertraline (SERT), a widely used antidepressant, poses an environmental challenge due to its persistence, potential toxicity, and resistance to conventional wastewater treatment methods. In this context, this study conducted a comparative analysis of different Advanced Oxidation Processes (AOPs) applied to the degradation of sertraline in aqueous matrices. Ten articles published between 2020 and 2025 were evaluated, considering parameters such as removal efficiency, mineralization, residual toxicity, energy cost, and operational conditions. The methods studied included heterogeneous photocatalysis, Fenton and photo-Fenton processes, electrochemical techniques, and hybrid systems (UV/H₂O₂, UV/O₃, among others). The results showed significant variations among the AOPs, with degradation efficiency strongly dependent on the type of catalyst, pH, reaction time, and type of radiation. The electro-Fenton process stood out for its high efficiency (99%) and mineralization rate (98%), but it exhibited high energy costs. In contrast, methods such as the use of 3D ZnO under UV light demonstrated good efficiency and lower residual toxicity, suggesting greater environmental feasibility. However, the lack of quantitative data on toxicity and energy cost in several studies compromised the comparison and in-depth analysis of the processes. It is concluded that AOPs are promising for the degradation of sertraline, but their practical application requires a careful evaluation of mineralization efficiency, formation of by-products, and energy feasibility. Standardization of studies, inclusion of toxicological assays, and the development of reusable and sustainable catalysts are essential for advancing the large-scale application of these technologies.
- Cícero Coelho de Escobar
- Cássia Marilda Duarte Lima Bitencourt
- Luís Eduardo Tavares Martins