O POTENCIAL DO USO DE HIDROGEL DE CELULOSE BACTERIANA NA ADSORÇÃO E LIBERAÇÃO DE FÁRMACOS: UMA REVISÃO BIBLIOMÉTRICA
O POTENCIAL DO USO DE HIDROGEL DE CELULOSE BACTERIANA NA ADSORÇÃO E LIBERAÇÃO DE FÁRMACOS: UMA REVISÃO BIBLIOMÉTRICA
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DOI: 10.22533/at.ed.2832328125
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Palavras-chave: adsorvente, base polimérica, sustentável
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Keywords: adsorbent, polymeric base, sustainable
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Abstract: Bacterial cellulose hydrogel is a material with great potential in several areas due to the presence of pores, swelling capacity, non-toxicity, and ease of chemical modification. Several of these properties exist because polymer chains form three-dimensional networks and consequently can swell due to the presence of hydrophilic groups, even though they are insoluble in water, which makes them effective alternatives as adsorbents. This material is produced from bacteria, such as Komagataeibacter xylinus, and has a structure that facilitates the absorption of drug molecules. This hydrogel is highly biocompatible and capable of adsorbing/removing a variety of drugs, including antibiotics, analgesics and therapeutic agents, making it useful in the environmental field and in controlled release systems. Producing the hydrogel from bacteria is an environmentally sustainable approach, which makes it a friendly option for these applications. Therefore, hydrogels are emerging as possible adsorbent materials for polluting substances, and bacterial cellulose stands out as an ideal choice as a polymeric base for these adsorbents. Thus, this work is a systematic review covering the period from 1985 to 2023 of bacterial cellulose hydrogel in drug adsorption and its application in controlled drug release systems, offering significant benefits for the efficacy and safety of pharmaceutical treatments.
- Ariane Maria da Silva Santos Nascimento
- ARIANE MARIA DA SILVA SANTOS
- Albert Santos Silva
- Érico Rego Dias
- Josy Anteveli Osajima Furtini
- Hernane da Silva Barud
- Edson Cavalcanti Silva-Filho