O IMPACTO DO ESTRESSE PSICOLÓGICO NA PSORÍASE: MECANISMOS FISIOPATOLÓGICOS E ESTRATÉGIAS TERAPÊUTICAS INTEGRADAS
O IMPACTO DO ESTRESSE PSICOLÓGICO NA PSORÍASE: MECANISMOS FISIOPATOLÓGICOS E ESTRATÉGIAS TERAPÊUTICAS INTEGRADAS
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DOI: https://doi.org/10.22533/at.ed.156132516049
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Palavras-chave: Psoríase; imunogenicidade, tratamento.
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Keywords: Psoriasis immunogenicity treatment.
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Abstract: Psoriasis is a chronic inflammatory skin disease influenced by immunological and psychological factors. Psychological stress activates the hypothalamic-pituitary-adrenal axis, exacerbating inflammation and reducing treatment efficacy. This study analyzed the pathophysiological mechanisms linking stress and psoriasis, highlighting new therapeutic approaches, such as biosimilars and gut microbiota modulation. The research suggests that stress management, combined with biological therapies, can optimize clinical outcomes and improve patients' quality of life.
- Paulo Jorge da Silva Campos Filho
- Isabella Vidal de Souza
- Natália Barreto e Sousa