NUTRIENTES ANTIOXIDANTES NA PREVENÇÃO E TRATAMENTO DA SÍNDROME METABÓLICA: UMA REVISÃO INTEGRATIVA

• DOI: https://doi.org/10.22533/at.ed.1782515105

• Palavras-chave: Síndrome Metabólica, Antioxidantes, Nutrição, Dietoterapia

• Keywords: Metabolic Syndrome, Antioxidants, Nutrition, Diet Therapy

• Abstract: INTRODUCTION AND OBJECTIVE: Metabolic syndrome is a condition that encompasses several pathologies, such as central obesity, high blood pressure, elevated triglyceride levels, increased fasting blood glucose, and reduced levels of high-density lipoprotein (HDL-c). Its incidence has risen over the years, along with mortality associated with cardiovascular diseases. Therefore, the aim of this study is to analyze the effects of antioxidant nutrient intake in individuals with metabolic syndrome, highlighting its relevance in the prevention and/or treatment of this disorder. METHODS: This study is an integrative literature review with a qualitative approach, aimed at identifying the benefits of antioxidant nutrient intake in the prevention and treatment of metabolic syndrome. The study followed five main stages: formulation of the guiding question, search and selection of articles, critical analysis, integration, and presentation of results. Searches were conducted in the BVS, Google Scholar, PubMed, and Science Direct databases, using DeCS descriptors combined with the Boolean operators AND and OR. Studies published between 2018 and 2025, in Portuguese and English, involving individuals with metabolic syndrome, were included. RESULTS AND DISCUSSION: After data analysis, only ten studies met the inclusion criteria, providing data relevant to the topic and organized into tables containing the most pertinent information for the study. Natural antioxidants such as flavonoids, curcumin, resveratrol, quercetin, and vitamin C demonstrated beneficial effects on metabolic parameters of metabolic syndrome by reducing oxidative stress, inflammation, and insulin resistance. The studies reported improvements in lipid profile, blood pressure, and liver function, with particular emphasis on flavonoids and the polyphenolic fraction of bergamot. Compounds such as curcumin and lycopene also exhibited antioxidant and cardioprotective potential. CONCLUSION: Antioxidant components are increasingly being studied as complementary strategies in the treatment and prevention of metabolic syndrome. These natural antioxidants help mitigate the pathophysiological conditions of the syndrome through a diet rich in foods containing these compounds. Therefore, further studies are needed to provide greater clarification regarding the potential of these compounds, the appropriate doses required to achieve beneficial effects, and possible contraindications.