NOVOS ANTICOAGULANTES ORAIS E SUAS EFICÁCIAS: UMA BREVE ANÁLISE NA LITERATURA ATUAL
NOVOS ANTICOAGULANTES ORAIS E SUAS EFICÁCIAS: UMA BREVE ANÁLISE NA LITERATURA ATUAL
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DOI: 10.22533/at.ed.14923041212
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Palavras-chave: Novos anticoagulantes orais, Eficácia, Tromboembolismo, Sangramento.
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Keywords: New oral anticoagulants, Efficacy, Thromboembolism, Bleeding.
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Abstract: Oral anticoagulants play a crucial role in the prevention and treatment of thromboembolic diseases. With scientific advances in the 21st century, new oral anticoagulants have emerged that offer advantages over traditional anticoagulants. The objective of this review is to evaluate the effectiveness of these new products compared to traditional anticoagulants, observing their ability to prevent thromboembolic events and their safety in relation to bleeding risks. Therefore, randomized clinical studies and systematic reviews were selected that examined the effectiveness of new oral anticoagulants compared to traditional ones. Studies published in the last 15 years focusing on patients with thromboembolic diseases were included. The studies analyzed showed that new oral anticoagulants, such as direct factor non-valvular atrial fibrillation, deep vein thrombosis and pulmonary embolism. Furthermore, these new medications have some significant advantages over traditional anticoagulants, such as less need for frequent monitoring of blood clotting, fewer drug interactions and a comparable or even superior safety profile, with a lower risk of serious intracranial bleeding. However, it should be noted that the studies also highlight the importance of individually evaluating each patient, considering aspects such as age, renal function, risk of bleeding and possible drug interactions, before prescribing a specific oral anticoagulant. Based on the evidence, new oral anticoagulants are effective in preventing thromboembolic events, offering advantages over traditional anticoagulants. These therapeutic options offer convenience for patients with non-valvular atrial fibrillation, deep vein thrombosis and pulmonary embolism. However, it is essential to consider the individual characteristics of each patient and carefully evaluate the risks and benefits before starting treatment with a new oral anticoagulant.
- Arthur Monteiro Batista
- Álvaro Ian Pereira Bezerra Feitosa
- Júlia Passos Rufino
- Maria Eduarda de Sousa Vieira
- Therezza Inácia Martins Gomes Leite
- Maria Victoria de Souza Carvalho
- Helane Pereira Melo
- Anna Lira Soares Falcão
- Nara Cardoso Rodrigues
- Ana Heloisa de Castro Macedo Paes
- Vicente Alves da Silva Portelada
- Renan Rios da Costa Cruz
- Maria Paula Silveira Brito
- Isabelle Carvalho de Melo Lima
- Raylton Jansen e Silva Segundo