Metalofármacos como Estratégia Terapêutica para o Câncer: Novas Abordagens e Impactos Clínicos
Metalofármacos como Estratégia Terapêutica para o Câncer: Novas Abordagens e Impactos Clínicos
DOI: https://doi.org/10.22533/at.ed.630112526022
Palavras-chave: Compostos de coordenação, Liberação controlada de fármacos, Citotoxicidade, Doenças humanas
Keywords: Coordination compounds, Controlled drug release, Cytotoxicity, Human diseases
Abstract: Cancer is one of the leading causes of death worldwide, characterized by the uncontrolled proliferation of cancer cells that spread throughout the body. Treatment involves surgery, radiotherapy, chemotherapy, and immunotherapy, but challenges such as drug resistance and toxicity persist. This chapter discusses the use of metallodrugs based on copper, gallium, ruthenium, platinum, and gold, in the treatment of cancer, exploring mechanisms of action and therapeutic advances, including controlled release systems, using nanomaterials.
- Jemmyson Romário de Jesus
- Angel Amado Recio Despaigne
- Wesley Clayton Primarte Aquino
- Marcos Vinicius de Sousa Pereira