MEDICINAL PLANTS FOR HYPERTENSION – AN OVERVIEW OF SYSTEMATIC REVIEWS
Atena
MEDICINAL PLANTS FOR HYPERTENSION – AN OVERVIEW OF SYSTEMATIC REVIEWS
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DOI: 10.22533/at.ed.62819131111
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Palavras-chave: Atena
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Keywords: hypertension, complementary therapies, medicinal plants, overview, systematic review
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Abstract:
Hypertension is a well-known
risk factor for cardiovascular disease and
mortality. Medicinal plants are the source of
many drugs and can possibly offer solutions
to antihypertensive therapy. An overview of
systematic reviews was undertaken. A sensitive
search was conducted in nine databases,
including publications published from January
2006 until November 2016. Systematic Reviews
(SR) that have studied the effect of medicinal
plants in the treatment of hypertensive patients
were selected. The outcomes searched were
cardiovascular morbimortality, antihypertensive
effect, quality of life and collateral effects.
SRs were evaluated by AMSTAR. 41 SR were
selected. 23 conducted meta-analysis. 51%
of SR were assessed as having good quality.
Trials included in SRs have short duration,
and cardiovascular outcomes could not be
investigated. Only one SR evaluated quality
of life. There is moderate quality evidence
that garlic, green tea, black tea and flaxseed,
decrease slightly blood pressure. There are
weak evidence that Hibiscus sabdariffa, Nigella
sativa, beetroot, cacao products, grape seed
extract, grape juice and Salvia hispanica (chia)
have a positive effect of reducing slightly blood
pressure. Current evidence points to absence
of significant effect in blood pressure of Panax
spp. (ginseng), Ginkgo biloba, Crataegus
monogyna (hawtorn), Ribes nigrum and Pinus
pinaster (Picnogenol®). There are no convincing
evidence for the use of medicinal plants as a
substitute to the usual antihypertensive drugs,
however, some of them can be included in dietetic
strategies, as complementary management of
hypertension.
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Número de páginas: 15
- Eno Dias de Castro Filho
- Vitor Camilo Cavalcante Dattoli
- Julio Baldisserotto
- Marcos Krahe Edelweiss