INTERAÇÃO ENTRE SUPLEMENTAÇÃO DE VITAMINA A, VACINAÇÃO CONTRA O SARAMPO E MORTALIDADE INFANTIL: UMA REVISÃO DE LITERATURA
INTERAÇÃO ENTRE SUPLEMENTAÇÃO DE VITAMINA A, VACINAÇÃO CONTRA O SARAMPO E MORTALIDADE INFANTIL: UMA REVISÃO DE LITERATURA
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DOI: https://doi.org/10.22533/at.ed.03124170513
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Palavras-chave: sarampo; vacina; mortalidade.
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Keywords: measles; vaccine; mortality.
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Abstract: NVAS is a strategy implemented in African countries to reduce infant mortality, especially in areas with vitamin A deficiency and infectious disease burden. However, recent studies have raised concerns about its interaction with measles vaccination (MV), suggesting unexpected effects on the immune response to MV, especially gender-dependent. Measles vaccination is crucial, drastically reducing measles-related mortality rates and having nonspecific effects that decrease infant mortality from other causes, especially when administered early. The study was an integrative literature review, analyzing articles published between 2013 and 2023, in English or Portuguese. 1.798 articles were considered in the initial analysis, of which 12 were selected based on inclusion criteria, after excluding duplicate articles and those that did not fit the topic. The interaction between MV and vitamin A supplementation is being explored, with varying results by gender. Measles vaccination coverage is still a challenge, especially in areas with fragile health systems, requiring strategies such as community campaigns. The role of vitamin A in modulating the immune response to vaccines, including measles, is complex and needs further research. Community participation is essential for the success of vaccination programs. In summary, NVAS, MV, and vitamin A supplementation have significant implications for child health and vaccine efficacy, requiring further studies and improvements in public health programs.
- João Luís Veiga Rangel
- Paula Pitta de Resende Côrtes