INFECÇÕES EM PACIENTES QUEIMADOS: PREVALÊNCIA MANEJO E ESTRATÉGIAS INOVADORAS DE PREVENÇÃO
INFECÇÕES EM PACIENTES QUEIMADOS: PREVALÊNCIA MANEJO E ESTRATÉGIAS INOVADORAS DE PREVENÇÃO
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DOI: https://doi.org/10.22533/at.ed.0641325250415
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Palavras-chave: Lesões por queimadura, Infecção, Antimicrobianos, Manejo de feridas por queimadura
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Keywords: “Burn injury”; “Infection”; “Antimicrobials”; “Burn wound management”
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Abstract: Burn wound infections represent one of the main clinical challenges in hospital settings, requiring a multidimensional approach for effective management. This article reviews evidence on emerging therapeutic interventions and preventive strategies in the treatment of infected burn wounds. A literature review was conducted using major medical databases with the following descriptors: “burn injury,” “infection,” “antimicrobials,” “burn wound management”, combined using the Boolean operator “AND”. All articles published between 2015 and 2025 were included in the primary analysis. Innovative technologies, such as the use of mesenchymal stem cells and regenerative therapies, show promising potential, although they still face limitations in terms of standardization and clinical applicability. Supplementation with antioxidants and glutamine has shown benefits in supporting wound healing, but current studies lack methodological homogeneity. The role of probiotics—traditionally applied to gastrointestinal conditions—also stands out, with growing evidence supporting their antimicrobial and wound-healing effects in infected wounds. Bacteriophage therapy, although still in early stages of clinical application, has demonstrated favorable outcomes in experimental models and in studies combining phages with antibiotics, underscoring its potential as an alternative to conventional antibiotic therapy. Proper selection of wound dressings, environmental hygiene, and the strict use of Personal Protective Equipment (PPE) remain essential for infection prevention. It is concluded that, despite recent advances, further standardized and long-term clinical studies are necessary to establish the efficacy and safety of these innovative approaches in managing infected burn wounds.
- Vinicius Sousa Dias
- Natália Barreto e Sousa
- Daniel de Oliveira Meireles
- Camille Freitas de Araújo
- Gabrielly Blosson Silva Sepulvida Pereira