IMUNOGENICIDADE E SEGURANÇA DA VACINA CONTRA A FEBRE AMARELA: IMPACTOS E PERSPECTIVAS GLOBAIS
IMUNOGENICIDADE E SEGURANÇA DA VACINA CONTRA A FEBRE AMARELA: IMPACTOS E PERSPECTIVAS GLOBAIS
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DOI: https://doi.org/10.22533/at.ed.658152520057
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Palavras-chave: Febre amarela; vacina; imunidade.
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Keywords: Yellow fever; vacines; immunity
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Abstract: Yellow fever is a highly lethal arboviral disease, and its prevention relies heavily on vaccination. This article reviews the vaccine's immunological aspects and safety, highlighting its effectiveness in inducing protective immunity and challenges related to adverse events. Fractional-dose strategies proved effective during shortages, maintaining adequate protection levels. However, vaccine hesitancy and logistical barriers hinder vaccination coverage in vulnerable populations. The study concludes that the yellow fever vaccine is crucial for global public health, despite challenges that require continuous improvement and research strategies.
- Mariana Garuffe
- Natália Barreto e Sousa