IMPACTO DO TRATAMENTO COM CANABIDIOL NA FORMAÇÃO FETAL EM INFECÇÕES POR Aedes aegypti

• DOI: https://doi.org/10.22533/at.ed.9192519023

• Palavras-chave: Aedes aegypti; Canabidiol; Morfologia; malformações congênitas.

• Keywords: Aedes aegypti; Cannabidiol; Morphology; congenital malformations.

• Abstract: Aedes aegypti is a vector responsible for the transmission of the arboviruses Dengue, Zika and Chikungunya, which are constant challenges to public health, infecting millions of people annually. Chikungunya presents risk factors to pregnant women as it is associated with thrombocytopenia, while the Zika virus is directly associated with congenital defects that include serious malformations and neuropsychomotor delays caused by the virus mainly during the first trimester of pregnancy, in addition to the high incidence of cases of microcephaly associated with the disease.  Studies that associate the Zika Virus with fetal anomalies and diseases suggest that it has developed specific methods to overcome the trophoblastic defense by affecting the fetal neuronal tissue. Considering the severity of the disease, especially in the gestational period, which does not have any specific treatment, phytotherapy with cannabidiol, a derivative of Cannabis sativa, is considered a possible successful therapy, since the derivative has neuroprotective, cardioprotective and anti-inflammatories that can help reduce the damage associated with serious dengue, chikungunya and zika infections. The objective of this study was to analyze how cannabidiol could contribute to the treatment during fetal formation of infections caused by Aedes aegypti.