HIPOTIREOIDISMO SUBCLÍNICO - DESAFIOS DIAGNÓSTICOS, IMPACTO CLÍNICO E ABORDAGENS TERAPÊUTICAS: UMA REVISÃO DE LITERATURA
HIPOTIREOIDISMO SUBCLÍNICO - DESAFIOS DIAGNÓSTICOS, IMPACTO CLÍNICO E ABORDAGENS TERAPÊUTICAS: UMA REVISÃO DE LITERATURA
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DOI: https://doi.org/10.22533/at.ed.7532408106
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Palavras-chave: Hipotireoidismo subclínico, diagnóstico, tratamento.
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Keywords: Subclinical hypothyroidism, diagnosis, treatment.
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Abstract: Subclinical hypothyroidism (SCH) is a condition characterized by elevated TSH (thyroidstimulating hormone) levels with normal FT4 (free thyroxine) levels, affecting between 2% and 25% of the global population. Although often asymptomatic, SCH is associated with risks such as cardiovascular diseases, hypertension, dyslipidemia, and pregnancy complications like gestational hypertension and preeclampsia. Detecting SCH is challenging due to the absence of clear symptoms, making regular laboratory tests essential. Treatment with levothyroxine (LT4) is common, particularly in pregnant women, to mitigate complications. However, the efficacy of LT4 is debated, with some evidence suggesting limited benefits, especially in the elderly. The decision to initiate therapy should consider the presence of symptoms and comorbidities. Management of SCH should be personalized, taking into account individual characteristics and contextual factors to optimize clinical outcomes and quality of life.
- Luiza Felix da Silva Rocha
- Danielle Abbud Backer