FERRAMENTAS DE AVALIAÇÃO DA GRAVIDADE EM DOENÇAS AUTOIMUNES: UMA ANÁLISE DOS ÍNDICES SALT, SLE-DAS E PASI
FERRAMENTAS DE AVALIAÇÃO DA GRAVIDADE EM DOENÇAS AUTOIMUNES: UMA ANÁLISE DOS ÍNDICES SALT, SLE-DAS E PASI
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DOI: https://doi.org/10.22533/at.ed.656122624035
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Palavras-chave: Alopecia Areata. Doenças Autoimunes. Lúpus Eritematoso Sistêmico. Psoríase.
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Keywords: Alopecia Areata. Autoimmune Diseases. Systemic Lupus Erythematosus. Psoriasis.
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Abstract: Autoimmune diseases (AIDs) comprise a heterogeneous group of chronic conditions resulting from the loss of immunological self-tolerance and consequent attack on the body's own tissues. They have a multifactorial etiology involving genetic predisposition and environmental factors; diseases such as Systemic Lupus Erythematosus, Psoriasis, and Alopecia Areata present clinical courses marked by periods of remission and exacerbation. This study aims to analyze the application of specific indices (SALT, SLE-DAS, and PASI) in the assessment of the activity and severity of these diseases. This is characterized as a descriptive and analytical research, based on a bibliographic and documentary review of scientific articles, master's and doctoral dissertations, from 2016 to 2025. The study is based on an understanding of the pathophysiology of AIDs and the limitations of subjective clinical assessment, since the accuracy of the management of these diseases depends on standardized metrics. Thus, the use of these indices allows for the conversion of clinical observations into numerical data, reducing variability and enabling the measurable monitoring of disease progression and therapeutic response. Therefore, these indices are essential for determining medication adjustments, monitoring disease progression, and evaluating the long-term effectiveness of treatments in highly complex scenarios.
- Brenda de Araújo Barbosa
- Clara Beatriz Oliveira Santos
- Isabelle Maria Pessoa da Rocha
- Tarcio Aurélio Gomes de Abreu
- Eduardo Escórcio Lima Dourado
- Tiago Dias Rocha
- Débora Cavalcante Braz
- José Lopes Pereira Júnior
- CARLA SOLANGE AZEVEDO DE LUNA