Endophytic microorganisms were first mentioned in the early 19th century, but only at the end of the 20th century they became more relevant in scientific research. Microorganisms were believed to be neutral, that is, cause no benefits or harm to plants. However, over the years the benefits from plant-microorganism interaction, have been discovered and, in many cases, playing an important role in plant protection and development (Azevedo et al., 2000; Santos & Varavallo, 2011).

Currently, endophytic microorganisms are widespread in academia and have been used to improve agriculture, such as: phosphate solubilization, plant nutrition, plant growth promotion, among other advantages that are being discovered every day. Among the advantages of plant-microorganism interaction, pest control with endophytic entomopathogenic microorganisms is a technology in increasing development.