EFEITOS DA ROSUVASTATINA NO CONTROLE DA HIPERTENSÃO E DISLIPIDEMIA - ESTRATÉGIAS EVOLUTIVAS PARA A REDUÇÃO DO RISCO CARDIOVASCULAR: UMA REVISÃO DE LITERATURA
EFEITOS DA ROSUVASTATINA NO CONTROLE DA HIPERTENSÃO E DISLIPIDEMIA - ESTRATÉGIAS EVOLUTIVAS PARA A REDUÇÃO DO RISCO CARDIOVASCULAR: UMA REVISÃO DE LITERATURA
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DOI: https://doi.org/10.22533/at.ed.23024130814
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Palavras-chave: ROSUVASTATINA; HIPERTENSÃO; TRATAMENTO.
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Keywords: ROSUVASTATIN; HYPERTENSION; TREATMENT.
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Abstract: The article discusses the relationship between hypertension (HTN) and dyslipidemia as risk factors for cardiovascular diseases (CVD), emphasizing the importance of controlling these conditions to reduce morbidity and mortality. 226 articles were analyzed, and after inclusion and exclusion criteria, 25 articles were selected, as shown in the study's flowchart and table. Treatment adherence is essential, and the polypill has been shown to be effective in this regard. Studies have investigated different drug combinations, such as the atorvastatin/amlodipine and rosuvastatin/losartan polypills, demonstrating significant benefits in controlling blood pressure and lipid levels. For patients with acute coronary syndrome (ACS) and acute ischemic stroke (AIS), intensive statin therapy combined with dual antiplatelet therapy (DAPT) is crucial for preventing recurrent events. Additionally, the appropriate choice of antihypertensive medications in patients at risk of diabetes, combined with high-intensity statins, is important for reducing the risk of new-onset diabetes. Rosuvastatin has been effective in reducing central blood pressure and improving insulin sensitivity, highlighting its role beyond cholesterol reduction. The combination therapy of telmisartan/rosuvastatin has also been effective in controlling central blood pressure and lipid levels. In summary, the therapeutic approach for patients with HTN and dyslipidemia has evolved, with an emphasis on treatment adherence, effective combination therapies, and central blood pressure control. New therapeutic strategies continue to be explored to improve clinical outcomes and reduce cardiovascular risk in this patient population.
- Júlia Vitória de Souza
- Danielle Abbud Backer