DIFICULDADES NO DESENVOLVIMENTO DE VACINAS CONTRA O HIV
DIFICULDADES NO DESENVOLVIMENTO DE VACINAS CONTRA O HIV
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DOI: https://doi.org/10.22533/at.ed.3442405013
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Palavras-chave: HIV, VACINA, PROFILAXIA
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Keywords: HIV, VACCINE, PROPHYLAXIS
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Abstract: AIDS is an incurable disease that affects millions of people worldwide. Although significant advances have been made in understanding the virus and treating the disease, vaccination remains the best strategy for preventing HIV infection. However, the development of an effective HIV vaccine has been a challenge for scientists. Methodology: A narrative review of the scientific literature on the challenges in the development of prophylactic HIV vaccines was conducted. Data collection was carried out in scientific databases, including PubMed, Scopus, Web of Science, and Google Scholar, as well as through reference to books, specialized journals, government documents, and other relevant sources that met inclusion criteria. Results: The main difficulties faced by scientists in the quest for an effective HIV vaccine include the genetic variability of the virus, the lack of suitable animal models for pre-clinical studies, and the complexity of the human immune system. However, new technologies and therapeutic approaches are being developed to overcome these challenges and expedite progress in the field. Final Considerations: It is crucial to continue investing in research on HIV biology and the immune response of the human body to gain a better understanding of the interactions between the virus and the immune system and to identify new therapeutic targets. Additionally, it is essential to improve existing vaccination strategies and develop new therapeutic approaches for AIDS treatment.
- Maria Laura Santana
- Tibério Cesar Lima de Vasconcelos
- Cristiane Gomes Lima