DETERMINACIÓN DE LA FRECUENCIA DE PASEUDOMONAS AERUGINOSA Y SU RESISTENCIA ANTIBIÓTICA AISLADA EN MUSTRAS CLÍNICAS DE PACIENTES DE UN HOSPITAL DE SEGUNDO NIVEL
DETERMINACIÓN DE LA FRECUENCIA DE PASEUDOMONAS AERUGINOSA Y SU RESISTENCIA ANTIBIÓTICA AISLADA EN MUSTRAS CLÍNICAS DE PACIENTES DE UN HOSPITAL DE SEGUNDO NIVEL
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DOI: https://doi.org/10.22533/at.ed.2352406028
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Palavras-chave: Pseudomonas aeruginosa, resistencia antibiótica
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Keywords: Pseudomonas aeruginosa, antibiotic resistance
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Abstract: Introduction. Pseudomonas aeruginosa is one of the multidrug-resistant bacteria with the worst prognosis that has emerged as a pathogen of great hospital importance, is increasingly recognized as an emerging opportunistic pathogen of clinical relevance that causes of chronic and recurrent infections, and that has developed resistance to different groups of antibiotics. Due to its resistance to different antimicrobial agents, the options for an effective treatment have been limited. The management of patients with Pseudomonas aeruginosa infections has become difficult to control. The problem that is intended to be addressed in this research is the multi-resistance that Pseudomonas aeruginosa presents to various antibiotics. Objective. Determine the frequency of Pseudomonas aeruginosa and its isolated antibiotic resistance in clinical samples of patients from a second-level Mexican hospital. Methodology. In this study, 1418 clinical isolates were obtained from bone, secretions (secretion from wounds, ulcers), urine, and respiratory tract (endotracheal, endobronchial, and bronchial aspirates, sputum) from patients from a Mexican Hospital during the period July 2022 to December 2022. The isolates were identified by conventional biochemical tests and susceptibility testing was performed by Kirby Baüer. All the results obtained were analyzed by descriptive statistics. Results. Of 1418 samples processed, P. aeruginosa was isolated in 10% and showed more than 50% resistance to the antibiotics tested. The antibiotic with the greatest resistance was tigecycline at 100%, followed by meropenem at 44% and cefepim at 41%. Conclusion. This study shows the important participation of Pseudomonas aeruginosa as an etiological agent of nosocomial infections and underlines the importance of knowing its resistance mechanisms that will help to decide the best therapeutic strategy. All this information will greatly support taking the necessary measures in hospitals to prevent the spread of multidrug-resistant bacteria.
- Villagrán Padilla Claudy Lorena
- Ruiz Tagle Alejandro César
- López García Alma
- Rubio Lozada Ana Guadalupe