CLASSIFICAÇÃO DOS TUMORES DO SISTEMA NERVOSO CENTRAL PEDIÁTRICO E IMPACTOS NO NEURODESENVOLVIMENTO. UMA REVISÃO SISTEMÁTICA ATRAVÉS DA LITERATURA
CLASSIFICAÇÃO DOS TUMORES DO SISTEMA NERVOSO CENTRAL PEDIÁTRICO E IMPACTOS NO NEURODESENVOLVIMENTO. UMA REVISÃO SISTEMÁTICA ATRAVÉS DA LITERATURA
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DOI: https://doi.org/10.22533/at.ed.3122409094
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Palavras-chave: Neurodesenvolvimento, Pediatria, Sistema Nervoso central.
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Keywords: Neurodevelopment, Pediatrics, Central Nervous System.
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Abstract: Solid neoplasms that develop in the Central Nervous System (CNS) may originate from cells in the nervous tissue itself or be initiated by cancer cells from other tissues in the body that have settled in the CNS and triggered the development of a tumor mass. These diseases, whether benign or malignant, can usually grow, displace and compromise important structures in the neuroaxis. The impacts of solid tumors on neurodevelopment are directly related to tumor aggressiveness, the types of treatments associated with the location of the neoplasm and the age of the patient. In addition, due to the aggressive behavior of the tumor and the need for treatment, there may also be impacts related to oncological therapeutic interventions, such as neurosurgery, radiotherapy and chemotherapy, which in some cases leave sequelae in children's neurodevelopment. Such tumor factors often affect neural development and neural functions in children and adolescents. Therefore, knowledge in the area of pediatric neuro-oncology is extremely important to ensure the quality of life and safeguard the intellectual, emotional, motor and pedagogical capacity of children and adolescents, in addition to aiming to preserve neural abilities for the future life of these people. This is because neural abilities are anchored mainly in the earliest age groups of life. The classification of tumors of the Central Nervous System is complex, as they arise in a wide variety of tissues of the brain and spinal cord. Likewise, given the evolution and complications that tumors of the Central Nervous System imply for neurodevelopment, it is understood that the disease is complex, harmful and is caused by a diversity of factors and genetic alterations. In short, tumors of the CNS can have significant and profound impacts on pediatric neurodevelopment and must be handled appropriately.
- Adinei Abadio Soares
- Kassiane Boita Kappes
- Yghor Augusto da Rocha Ricardo
- Luan Lucena
- Carlos Sérgio Praça Consalter
- João Victor Garcia de Souza
- Matheus Chimelo Bianchini
- DEBORA TAVARES DE RESENDE E SILVA
- Débora Tavares de Resende e Silva