BIOPESTICIDAS NATURAIS: UMA REVISÃO DE LITERATURA SOBRE BIOINSETICIDAS, BIOHERBICIDAS E MODELAGEM APLICADA

• DOI: https://doi.org/10.22533/at.ed.835152512066

• Palavras-chave: Biopesticidas naturais; Produtos vegetais; Modelagem computacional; Agricultura sustentável.

• Keywords: Natural biopesticides; Plant-derived products; Computational modeling; Sustainable agriculture.

• Abstract: The expansion of Brazilian agribusiness has led to an increasing use of pesticides, resulting in environmental impacts, toxicological risks, and the development of resistance in target organisms. In this context, there is growing interest in sustainable alternatives for agricultural management, such as natural biopesticides. This chapter presents a comprehensive review of scientific literature on the use and development of biopesticides, with a particular focus on bioinsecticides and bioherbicides, as well as the role of computational modeling in this field. It discusses the main plant-derived compounds with insecticidal potential, including flavonoids, terpenoids, and glucosinolates, addressing their biological effects, mechanisms of action, and the most widely used extraction methods and efficiency evaluation techniques. Additionally, the chapter examines how computational modeling tools have contributed to predicting interactions between natural compounds and biological targets, facilitating the identification of promising molecules and optimizing the development of new biopesticides by reducing both time and costs. Despite their potential, the adoption of biopesticides still faces technical, regulatory, and economic challenges. The integration of basic research, technological innovation, and computational modeling is essential to enable the gradual replacement of synthetic pesticides with safer, more sustainable, and efficient solutions for agriculture.