BIOACTIVE VOLATILE COMPOUNDS OF GINGER LEAVES: A NOVEL PERSPECTIVE FOR AN UNDER-INVESTIGATED MATERIAL

• DOI: https://doi.org/10.22533/at.ed.3952424102

• Palavras-chave: Essential oil; Zingiber officinale; Leaves; Cytotoxicity activity; Functional ingredient.

• Keywords: Essential oil; Zingiber officinale; Leaves; Cytotoxicity activity; Functional ingredient.

• Abstract: For centuries, the rhizome of ginger (Zingiber officinale Roscoe) has been used for therapeutic purposes. In contrast, the aerial parts of this plant have received comparatively little attention. This study aimed to evaluate the essential oil of ginger leaves (EOL), with respect to both chemical composition and in vitro antioxidant, antibacterial, and cytotoxic activities. GC-MS analysis identified the presence of 14 compounds, among which the major compounds were beta- pinene (67.9%), eucalyptol (9.9%), and betaphellandrene (9.5%). In vitro antioxidant assays revealed IC50 values of 2702.7 and 2512.6 µg/mL for DPPH and ABTS radicals, respectively. The EOL also showed good cytotoxicity against colorectal adenocarcinoma cell line, and at 600 µL/mL inhibited 39.33% of the cells. Furthermore, in disc diffusion assays, the EOL showed best performance against Pseudomonas aeruginosa. Collectively, the results indicate that ginger EOL has considerable bioactivity and may have application potential as a functional ingredient, providing health benefits.