AVANÇOS TERAPÊUTICOS NA ESCLEROSE MÚLTIPLA O PAPEL DOS ANTICORPOS MONOCLONAIS E SUAS APLICAÇÕES CLÍNICAS
AVANÇOS TERAPÊUTICOS NA ESCLEROSE MÚLTIPLA O PAPEL DOS ANTICORPOS MONOCLONAIS E SUAS APLICAÇÕES CLÍNICAS
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DOI: https://doi.org/10.22533/at.ed.3781225070415
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Palavras-chave: Ocrelizumabe; esclerose múltipla; tratamento.
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Keywords: Ocrelizumabe; multiple sclerosis; treatment.
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Abstract: This article examines the impact of monoclonal antibodies in the treatment of Multiple Sclerosis (MS), focusing on ocrelizumab and natalizumab. It explores their pharmacological features, clinical efficacy, safety, and real-world application. The research also highlights the importance of biosimilars as a cost-effective alternative and the role of biomarkers in monitoring therapy. Home infusion is evaluated as a strategy to improve adherence and patient satisfaction. It concludes that monoclonal antibodies represent a therapeutic breakthrough in MS, promoting significant advances in disease control and quality of life.
- Gabriel El Alam Bighetti
- Ramon Fraga de Souza Lima
- Pedro Nascentes Soares
- Erick Montes da Silva Filho
- Edison Henrique da Costa Parente Martins
- Eduarda Rechuan Carvalho
- Gabrielle Balieiro Diniz
