AVANÇOS E DESAFIOS NA ABORDAGEM DO HELICOBACTER PYLORI: UMA REVISÃO BIBLIOGRÁFICA
AVANÇOS E DESAFIOS NA ABORDAGEM DO HELICOBACTER PYLORI: UMA REVISÃO BIBLIOGRÁFICA
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DOI: https://doi.org/10.22533/at.ed.59924211115
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Palavras-chave: H Pylori; infecção, tratamento.
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Keywords: H Pylori; infection; treatment
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Abstract: This article reviews therapeutic strategies for eradicating Helicobacter pylori (H. pylori) infection, a leading cause of gastrointestinal diseases such as chronic gastritis, peptic ulcers, and gastric cancer. The increasing resistance to antibiotics, particularly clarithromycin, poses a significant challenge, necessitating the development of new approaches. Among the explored alternatives are quadruple therapy with bismuth, probiotics, and new acid inhibitors like vonoprazan. The addition of agents such as Lacticaseibacillus rhamnosus and Saccharomyces boulardii has shown benefits in reducing side effects and increasing eradication rates. The article also addresses the impact of oral hygiene and reinfection in high-prevalence areas. Finally, it explores emerging therapies such as the use of immunoglobulins and antibacterial liquids, along with promising new therapeutic options under investigation, including vaccines, for more effective management of the infection and prevention of severe complications.
- Juliana Silveira Sola
- ROSSANO KEPLER ALVIM FIORELLI
- ANA CLARA PINHEIRO ANDRADE
- LUIZA REZENDE MANNA
- MARIANA ALFENA OSTWALD
- MARIA VICTORIA DA COSTA FARFAN
- MILLA DAUDT RIBEIRO