EVALUATION OF THE CLINICAL AND LABORATORY REPERCUSSIONS OF COVID-19 IN PATIENTS WITH LIVER CIRRHOSIS
EVALUATION OF THE CLINICAL AND LABORATORY REPERCUSSIONS OF COVID-19 IN PATIENTS WITH LIVER CIRRHOSIS
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DOI: 10.22533/at.ed.9452318126
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Palavras-chave: COVID-19, Cirrose Hepática, Epidemiologia.
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Keywords: COVID-19, Liver Cirrhosis, Epidemiology.
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Abstract: BACKGROUND: The COVID-19 pandemic managed, in a short time, to mark the history of science as one of the most relevant problems in recent decades, given that its mortality and morbidity is intensified in individuals with a pre-existing disease. Therefore, it takes more studies to make a correlation between some pathologies, such as hepatics diseases and COVID-19. OBJECTIVE: Thus, the present study aims to evaluate the clinical and laboratory repercussions in patients with liver cirrhosis who were infected by SARS-COV-2. METHODS: The research followed the ethical standards of the Nuremberg Code and the Declaration of Helsinki, and it is classified as a cross-sectional, prospective, and observational study. Epidemiological data, such as gender and age, patient perceptions about their own health, laboratory and/or image tests were analyzed. RESULTS: It was seen that asthenia was the most frequent post-COVID-19 symptom among the participants. In addition, about 8% of them reported damage in their health status, and 16% reported that it had no changes compared to pre-COVID-19. It was noticed that the laboratory parameters which showed most worsening was cholesterol, triglycerides, total bilirubin and Gamma-GT. Furthermore, there was a reduction in transamins and creatinine, an insignificant decrease in hemoglobin and no changes in the platelets. CONCLUSION: Ultimately, it can be concluded that patients with cirrhosis who survive COVID-19 may have no worsening of their underlying liver disease or long-term prognosis. It is important to carry out more studies that compare, in more detail, the interferences of COVID-19 in the natural history of liver cirrhosis.
- Elisa Carmo Viana
- Maria Clara Fonseca Santos
- Lucas Oliveira Mota
- Lizomar de Jesus Maués Pereira Moia