Após exposição oral Glifosato como se dão as alterações epiteliais renais - uma revisão da literatura

• DOI: https://doi.org/10.22533/at.ed.98924160113

• Palavras-chave: herbicida, rim, epitélio, contaminação, saúde pública.

• Keywords: herbicide, kidney, epithelium, contamination, public health.

• Abstract: The herbicide most used today in Brazil is glyphosate, from the organophosphate class. This is considered an agrochemical that has the potential to control weed growth. However, with the exacerbated use of glyphosate in agriculture, individuals who have direct or indirect contact with this herbicide can become contaminated and develop some dysfunctions in the body, such as changes in the renal epithelium. Furthermore, some studies have shown that specific kidney structures are affected by exposure to this herbicide. Among these, the epithelium of the distal and proximal tubules of the kidney and the glomerulus stand out. In the renal tubules it is possible to notice the promotion of necrosis and fibrosis, while at the glomerular level, fragmentation, swelling, inflammation, necrosis and also a loss in filtration can be observed. In addition to these changes, a decrease in kidney weight is also seen. Therefore, it is possible to see that contamination through glyphosate is a public health risk, as this herbicide can cause a series of dysfunctions in the body and affect several functions essential to the well-being of human beings. Therefore, it is necessary to study the risks that this pesticide poses to humans, as its use has been widespread and is still being used throughout the country, causing harm to health