APLICAÇÕES DO ÁCIDO GÁLICO NO MANEJO DE HIPERCROMIAS: UMA REVISÃO DA LITERATURA
APLICAÇÕES DO ÁCIDO GÁLICO NO MANEJO DE HIPERCROMIAS: UMA REVISÃO DA LITERATURA
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DOI: 10.22533/at.ed.2042314119
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Palavras-chave: Antioxidante. Hiperpigmentação. Tirosinase. Expressão Gênica. Taninos.
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Keywords: Antioxidant. Hyperpigmentation. Tyrosinase. Gene expression. Tannins.
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Abstract: The skin, being the largest organ in the human body, plays a crucial role not only in protecting the organism but also in aesthetics and self-esteem. Understanding the mechanisms that affect its health and appearance is fundamental. In this context, gallic acid, a phenolic compound found in various plants, has gained prominence in dermatological research due to its properties as a depigmenting agent. This study conducted an integrative review of scientific articles available on the Science Direct and PubMed databases with the aim of critically analyzing the findings related to gallic acid and its influence on the treatment of hyperpigmentation. The results of this analysis revealed an impressive range of benefits of gallic acid for skin health. Firstly, its ability to inhibit the activity of tyrosinase, a central enzyme in melanin biosynthesis, stood out. This implies that gallic acid can be a powerful ally in skin lightening and in the treatment of hyperpigmentation issues, such as dark spots. Additionally, gallic acid demonstrated a potent antioxidant effect, combating free radicals and protecting the skin from damage caused by the sun and premature aging. This phenolic compound not only showed its effectiveness in keeping the skin looking young but also exhibited potential in skincare products. Its ability to regulate genes involved in melanogenesis and antioxidant defense highlights its value in aesthetic dermatology. This integrative review emphasized gallic acid as a promising player in the skincare landscape. Its multifunctional properties and potential benefits open doors to a range of applications in skincare products and treatments, promoting both skin health and aesthetics. However, further research is needed to fully explore its spectrum of action and develop even more effective formulations.
- Camila Fortes Castelo Branco Magalhães
- Maria Beatriz Leal dos Santos
- José Gabriel Fontenele Gomes
- Gabriel Felipe Alcobaça Silva
- Giovanna Carvalho Sousa Silva
- Rosilene Ribeiro de Sousa
- Vitória Maria Santos Figueiredo
- André Luiz Pinheiro de Moura
- Francisco Gesley de Sousa Abreu
- Irisvaldo Lima Guedes
- Jordanna di Paula Santos Sousa
- André Luis Menezes Carvalho