APLICACIÓN DE LA ELECTROQUÍMICA EN EL CAMPO FARMACÉUTICO

• DOI: 10.22533/at.ed.7782317108

• Palavras-chave: principios activos, electrodos serigrafiados, electroquímica, microelectroanálisis

• Keywords: active ingredients, screen-printed electrodes, electrochemistry, microelectroanalysis

• Abstract: At present, electrochemistry is one of the most applied methodologies for the identification and analysis of analytes, given its multiple benefits and facilities. Several studies have shown the high detection capacity, as well as the reproducibility and sensitivity that this technique provides. Not only is a positive performance attributed for its analysis effectiveness, but also in the improvement and minimization of costs; ease of transport allowing development in a laboratory or on site. Therefore, it is proposed to verify the application of this methodology with a focus on the pharmaceutical field for the detection of active principles based on review articles and experiments in order to know the most used and effective techniques, detection capacity and advantages. The results denoted that cyclic voltammetry, differential pulse and square wave techniques are the most applicable and effective in determining pharmacological analytes. Acetaminophen and ibuprofen were mainly detected, allowing to obtain oxidation peaks that suggest the presence of these with a linear correlation of 99%. The use of screen- printed electrodes improves detection at minimal sample concentrations. It is concluded that electrochemistry is useful for the determination of active analytes, obtaining advantages in their use due to low costs, ease, and improvement of these. The reports they present a method as a powerful technique for possible studies in the pharmaceutical field and other considerations, a feasible alternative, friendly to the environment.