USE OF PROBIOTICS IN ATOPIC DERMATITIS IN CHILDREN
Atopic dermatitis (AD) is a dermatological disease that usually begins in childhood and is inflammatory in nature. It is characterized by a multifactorial cause, involving genetic and environmental factors, often associated with a history of atopy. The diagnosis of AD is clinical and is characterized by erythematous plaques, oedema, vesicles and itching in the area. Treatment varies according to the level and severity of the lesions and usually involves topical corticosteroids, antihistamines, systemic steroids and antibiotics. However, prolonged use of these drugs can lead to side effects. The use of probiotics has been studied as an approach to controlling AD in children. Aim: To study the impact of using probiotics as a therapeutic strategy to treat atopic dermatitis in children. Method: Integrative literature review carried out with the findings of the PubMed database, considering studies published between 2019 and 2024. Only randomized studies were selected. The keywords used were "probiotics", "atopic dermatitis" and "children". Results: According to the findings, probiotics act as immunomodulators and are capable of reducing the inflammatory response by acting to strengthen dermal barrier. As a result, in most studies there was a reduction in the SCORAD system, which classifies moderate to severe AD. Conclusion: The study revealed important results in relation to the use of probiotics as an intervention for AD. However, more comprehensive and standardized studies are still needed to develop consistent protocols.
USE OF PROBIOTICS IN ATOPIC DERMATITIS IN CHILDREN
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DOI: https://doi.org/10.22533/at.ed.1595925300113
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Palavras-chave: atopic dermatitis, children, probiotic
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Keywords: atopic dermatitis, children, probiotic
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Abstract:
Atopic dermatitis (AD) is a dermatological disease that usually begins in childhood and is inflammatory in nature. It is characterized by a multifactorial cause, involving genetic and environmental factors, often associated with a history of atopy. The diagnosis of AD is clinical and is characterized by erythematous plaques, oedema, vesicles and itching in the area. Treatment varies according to the level and severity of the lesions and usually involves topical corticosteroids, antihistamines, systemic steroids and antibiotics. However, prolonged use of these drugs can lead to side effects. The use of probiotics has been studied as an approach to controlling AD in children. Aim: To study the impact of using probiotics as a therapeutic strategy to treat atopic dermatitis in children. Method: Integrative literature review carried out with the findings of the PubMed database, considering studies published between 2019 and 2024. Only randomized studies were selected. The keywords used were "probiotics", "atopic dermatitis" and "children". Results: According to the findings, probiotics act as immunomodulators and are capable of reducing the inflammatory response by acting to strengthen dermal barrier. As a result, in most studies there was a reduction in the SCORAD system, which classifies moderate to severe AD. Conclusion: The study revealed important results in relation to the use of probiotics as an intervention for AD. However, more comprehensive and standardized studies are still needed to develop consistent protocols.
- Luis Angelo Trovo
- Natália Vasconcelos Carvalho
- Ana Helena Fernandes da Silva Bueno Miranda
- Thiago Milani Muniz de Souza