USE OF LIRAGLUTIDE FOR WEIGHT LOSS IN OBESE OR OVERWEIGHT PATIENTS ASSOCIATED WITH COMORBIDITIES: A LITERATURE REVIEW

• DOI: 10.22533/at.ed.15938823181010

• Palavras-chave: Liraglutide; Obesity; Weight loss; Diabetes Mellitus

• Keywords: Liraglutide; Obesity; Weight loss; Diabetes Mellitus

• Abstract:

  INTRODUCTION: Obesity and overweight are hotly debated topics, as they are risk factors for several diseases and their current treatment and prevention are inefficient. In this sense, Liraglutide, initially used to treat type 2 diabetes mellitus, is now being investigated with a view to weight loss. OBJECTIVE: To review the action and effectiveness of using Liraglutide in non-diabetic patients for weight loss, comparing it with other treatments for the same purpose, in different studies. METHODS: Integrative literary review of articles from the PubMed and Lilacs databases, using as keywords the terms “Liraglutide”, “Weight Loss”, “Obesity” and “Diabetes Mellitus” published between 2016 and 2021. RESULTS: Among the 11 articles used, it was observed that Liraglutide can promote increased satiety and can cause changes in the gastrointestinal tract, consequently causing a reduction in food intake and loss of body weight. However, it also raised concerns related to several factors and adverse reactions resulting from its use. CONCLUSION: Liraglutide has been shown to be effective for weight loss in non-diabetic patients, especially when combined with dietary re-education and behavioral therapy. However, as it is a relatively new medication, attention must be paid to possible adverse reactions.