TREATMENTS FOR OVULATION IN CASES OF POLYCYSTIC OVARY SYNDROME

• DOI: https://doi.org/10.22533/at.ed.15952025240410

• Palavras-chave: SOP; Treatments; Management.

• Keywords: SOP; Treatments; Management.

• Abstract:

  This study addresses Polycystic Ovarian Syndrome (PCOS), a complex endocrine-metabolic condition that affects women of reproductive age, representing a significant challenge for reproductive and metabolic health. It is characterized by dysfunctions such as menstrual irregularity, anovulation, hyperandrogenism and metabolic disorders, notably insulin resistance, increasing the risk of long-term complications. This is a qualitative, retrospective and cross-sectional integrative literature review, which analyzed scientific articles from the PubMed and Virtual Health Library databases, obtaining a total of 11 articles for analysis. The review explores the multifactoriality of anovulation in PCOS and various therapeutic approaches to associated infertility. It highlights studies comparing the efficacy of ovulation inducers such as Letrozole and Clomiphene Citrate, their combinations, the impact of different doses and stimulation protocols, as well as the role of insulin sensitizers such as Metformin and Inositols (Myo-inositol and D-chiro-inositol), evaluating their benefits and the importance of specific proportions. Predictive factors such as Anti-Müllerian Hormone (AMH) levels and the need to update diagnostic criteria for a more integrated approach are also discussed. The study highlights the complexity of PCOS management, underlining the importance of individualized therapeutic approaches and ongoing research to optimize treatments and diagnostic criteria in order to improve reproductive and metabolic outcomes for patients.