THERAPEUTIC RESULTS OF THE HPV VACCINE

• DOI: https://doi.org/10.22533/at.ed.1595172511042

• Palavras-chave: Therapeutic results, HPV vaccine, Prevention, Human papillomavirus.

• Keywords: Therapeutic results, HPV vaccine, Prevention, Human papillomavirus.

• Abstract:

  Objective: To analyze the therapeutic results of the HPV vaccine, evaluating its efficacy in preventing infections, precancerous lesions and the impact on the incidence of cancers associated with the virus. Methodology: A bibliographic review was carried out in the PubMed - MEDLINE database, using the search terms "therapeutic", "HPV vaccines", "results" and their combinations. A total of 28 articles were selected for detailed analysis. Discussion: Large-scale vaccination is potentially associated with a reduction in HPV-related infections and lesions. Recent studies highlight immunotherapy combined with the quadrivalent vaccine as a promising advance in the treatment of recurrent or metastatic cervical cancer. In addition, challenges such as vaccine hesitancy and lack of knowledge about immunization remain significant barriers, often influenced by geographical and economic factors. The durability of the immune response induced by HPV vaccines has been a focus of new research, reinforcing their long-term efficacy. Final considerations: The importance of implementing awareness campaigns and community strategies, especially in low- and middle-income countries, to increase vaccination coverage is highlighted. However, it is essential to recognize the complexity of the issue and the need for further research to fully elucidate the benefits of vaccination and establish robust guidelines for the population.