SURGICAL TECHNIQUES IN THE TREATMENT OF INSULINOMAS: A COMPREHENSIVE REVIEW OF APPROACHES, EFFECTIVENESS AND IMPACTS ON QUALITY OF LIFE

• DOI: https://doi.org/10.22533/at.ed.159442409016

• Palavras-chave: insulinoma; neuroendocrine tumor; pancreas; surgical technique; treatment.

• Keywords: insulinoma; neuroendocrine tumor; pancreas; surgical technique; treatment.

• Abstract:

  Objective: Analyze and synthesize the surgical approaches used in the treatment of insulinomas, highlighting their effectiveness, complications and impacts on patients' quality of life. Methods: A Literature Review was carried out through searches in the PubMed database. Among the 93 articles identified, 11 studies were selected that met the established inclusion criteria. Results: The various research modalities analyzed converge to the conclusion that complex surgeries are the only curative treatment option for insulinoma. The location of the tumor, its proximity to vital pancreatic structures and the functionality of the mass represent crucial criteria that guide the choice of surgical techniques. Open surgery, with enucleation of the tumor, using palpation and intraoperative ultrasound to identify the mass, stands out as the most effective alternative in the treatment of insulin-producing pancreatic tumors. This approach aims to optimize clinical results and quality of life for patients. Conclusion: There is a pressing need to expand the scope of research into the treatment of insulinoma, especially in cases of multiple tumors, aiming to provide a more in-depth understanding of the best therapeutic options and the establishment of appropriate guidelines.