Systematic Lymphadenectomy versus Sentinel Lymph Node Mapping in Endometrial Cancer: A Narrative Review of Current Evidence, Outcomes and Guidelines
Systematic Lymphadenectomy versus Sentinel Lymph Node Mapping in Endometrial Cancer: A Narrative Review of Current Evidence, Outcomes and Guidelines
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DOI: https://doi.org/10.22533/at.ed.15953325201113
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Palavras-chave: -
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Keywords: Endometrial cancer; sentinel lymph node; lymphadenectomy; morbidity; survival; quality of life.
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Abstract: Endometrial cancer (EC) incidence is rising worldwide, increasing the need for accurate lymph node assessment. Recent advances have shifted surgical staging from systematic lymphadenectomy to sentinel lymph node (SLN) mapping, which aims to preserve oncologic safety while reducing morbidity. This narrative review summarizes evidence from 2018–2025 showing that lymphadenectomy offers no survival benefit and leads to higher rates of lymphedema and lymphoceles. SLN mapping provides high diagnostic accuracy and fewer complications, with comparable survival outcomes. Remaining challenges include lower mapping success in obesity and limited access to minimally invasive technology in Brazil, underscoring the need for expanded training and infrastructure.
- Gabryella Silveira Cardoso
- Alyne Niyama
- Ana Claudia Alves da Silva
- Romena Leão Azevedo Catao
- Marina Zamuner Correia dos Santos