MAGNESIUM SULFATE IN THE TREATMENT OF PRE-ECLAMPSIA AND ITS ADVERSE EFFECTS

• DOI: 10.22533/at.ed.15932523030410

• Palavras-chave: Gestational hypertension. Pre eclampsia. Eclampsia. Magnesium sulfate.

• Keywords: Gestational hypertension. Pre eclampsia. Eclampsia. Magnesium sulfate.

• Abstract:

  Introduction: One of the most serious complications of pre-eclampsia is the occurrence of a seizure, called eclampsia. Magnesium sulfate is the first choice in the treatment of preeclampsia, despite the risk of toxicity and possible adverse effects. Objective: To analyze the evidence on the use of magnesium sulfate in preeclampsia and address its main adverse effects. Methodology: A bibliographic search was carried out in three databases from 2017 to 2022 using the descriptors: “pre-eclampsia”, “magnesium sulfate”, “preeclampsia”, “magnesium sulfate”. Outcome: Studies show that magnesium sulfate has proven to be a superior agent than other drugs in reducing the risk of eclampsia. The main regimens for using magnesium sulfate are Pritchard's and Zuspan's. Its use carries a small risk of magnesium intoxication. Side effects include: flushing, sweating, nausea, drowsiness, headache, blurred vision, loss of patellar reflex, respiratory paralysis and even cardiac arrest. Conclusion: Prophylaxis of eclamptic seizures with magnesium sulfate is a milestone in the clinical management of preeclampsia. When administered, careful monitoring for signs of intoxication is paramount.