LOCKING SOLUTIONS FOR SHORT-STAY HEMODIALYSIS CATHETERS - An Integrative Review

• DOI: https://doi.org/10.22533/at.ed.51572826020410

• Palavras-chave: Catheter. Hemodialysis. Locking solution.

• Keywords: Catheter. Hemodialysis. Locking solution.

• Abstract:

  Objective: To comparatively analyze the effects and complications of hemodialysis catheter lock solutions, focusing on sodium citrate and heparin, highlighting their advantages and disadvantages in clinical practice. Method: A systematic review of studies published in the last ten years was conducted, using the descriptors "catheter," "hemodialysis," and "blocking solution" in two languages (English and Portuguese) in the DeCS/VHL and MeSH databases. Studies were selected according to the PICO strategy and subjected to detailed analysis. The review included six studies comparing the two lock solutions in patients undergoing hemodialysis, organized in a table to facilitate comparison of the findings. Results: The findings indicated that 4% sodium citrate proved to be an effective alternative to heparin, particularly in reducing infectious complications and maintaining catheter patency. However, some studies did not identify significant differences in catheter longevity or the incidence of infections, suggesting the need for further research to define the optimal application of each solution. Conclusion: Sodium citrate may be a viable option in patients at increased risk of catheter dysfunction, but the variability in outcomes highlights the need for additional studies to guide its use in different clinical contexts.