Acute cholestatic syndrome caused by paracoccidioidomycosis in an immunosuppressed patient – A case report.

• DOI: https://doi.org/10.22533/at.ed.51571252300714

• Palavras-chave: Paracoccidioidomycosis, cholestatic syndrome, HIV, systemic mycosis, lymphadenopathy.

• Keywords: Paracoccidioidomycosis, cholestatic syndrome, HIV, systemic mycosis, lymphadenopathy.

• Abstract:

  Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin America, caused by fungi of the genus Paracoccidioides. Its acute/subacute form can present with disseminated lymph node involvement and, more rarely, with extrinsic compression of the biliary tree, mimicking obstructive hepatobiliary di-seases. We describe the case of a young HIV-positive patient with controlled viral load who developed acute cholestatic syndrome of initially unclear etiology. The diagnosis of PCM was confirmed only after surgical investigation and histopathological study. This report reinforces the importance of PCM as a dif-ferential diagnosis in immunosuppressed patients with obstructive jaundice, even in the absence of classic signs of mycosis.